Peptide Calculator Plus
GLP-1 / Weight Management

Tirzepatide Dosage Calculator

A dual GIP/GLP-1 receptor agonist used for type 2 diabetes and weight management. Acts on both incretin pathways for enhanced metabolic effects compared to GLP-1-only agonists.

Also known as: Mounjaro, Zepbound, GIP/GLP-1

Peptide Reconstitution Calculator

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Tirzepatide -- A dual GIP/GLP-1 receptor agonist used for type 2 diabetes and weight management. Acts on both incretin pathways for enh...Route: Subcutaneous injection | Frequency: 1x per week | Half-life: ~5 days
Below typical range (2.50 mg - 15 mg)

Your Results

Concentration
2.5 mg/mL
= 2500 mcg/mL
Volume to Draw
0.10 mL
Syringe Units (U-100 insulin syringe)
10.0 units
100 units = 1 mL on a standard U-100 insulin syringe
Doses Per Vial
20 doses
at 250 mcg per dose from a 5mg vial
U-100 Insulin Syringe
0u
50u
100u
10.0 units
0.10 mL
Summary: Add 2 mL of bacteriostatic water to your 5mg vial. To get a 250 mcg dose, draw 0.10 mL (10.0 units) on a U-100 insulin syringe. This vial will provide 20 doses at this dosage.
For research purposes only. This calculator is a mathematical tool and does not constitute medical advice. Always consult with a qualified healthcare professional before using any peptide.

Tirzepatide Quick Reference

Typical Dose
2.50 mg - 15 mg
Frequency
1x per week
Route
Subcutaneous injection
Half-Life
~5 days
Common Vials
5 mg, 10 mg, 15 mg
Reconstituted Stability
Up to 28 days refrigerated
Note: Titrate slowly: start at 2.5 mg/week for 4 weeks minimum before increasing. The dual mechanism means potentially stronger GI side effects if titrated too quickly.

Tirzepatide Storage

Lyophilized: 2-8 C. Reconstituted: 2-8 C

Stability after reconstitution: Up to 28 days refrigerated. Always use bacteriostatic water for multi-use reconstitution. Label the vial with the reconstitution date and discard after the stability period.

Tirzepatide Frequently Asked Questions

Start at 2.5 mg/week for 4 weeks, then 5 mg for 4 weeks, 7.5 mg for 4 weeks, 10 mg for 4 weeks, 12.5 mg for 4 weeks, then 15 mg maintenance. Minimum 4 weeks at each step.
Adding 2 mL gives 5 mg/mL. For 2.5 mg, draw 0.5 mL (50 units). For 5 mg, draw 1 mL (100 units, a full insulin syringe). Consider using 1 mL for lower concentrations.
Tirzepatide targets both GIP and GLP-1 receptors (dual agonist), while semaglutide targets only GLP-1. Clinical trials showed tirzepatide produced greater weight loss on average (up to 22.5% vs 15% body weight).
At 2.5 mg/week: 4 weeks. At 5 mg/week: 2 weeks. At 10 mg/week: 1 week. Planning vial purchases around your titration schedule helps avoid waste.
Yes, but consult a healthcare provider for proper crossover dosing. Generally, you would stop semaglutide and begin tirzepatide at 2.5 mg the following week, then titrate up normally.
Nausea, diarrhea, decreased appetite, vomiting, and constipation are most common, especially during dose increases. These typically improve within 1-2 weeks at each dose level.

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